For the defects of crack, wrinkle and insufficient forming during the forming process of automobile front partition, based on the results of finite element simulation, three objective functions, namely local tensile fracture evaluation function, local wrinkle evaluation function and overall safety evaluation function, were constructed, and the defects in the forming process of the front partition were evaluated quantitatively. Then, the resistance coefficient of segmented drawbeads and the blank holder force were taken as the influencing factors in the multi-objective optimization, the test scheme was designed by the central composite test method, and the multi-objective optimization model between the influencing factors and the objective function was established. Furthermore, the optimized parameters were obtained with x1=0.4, x2=0.4, x3=0.35 and x4=130 kN, and the verified tests were conducted at the factory with the optimized process parameters to obtain the good quality front partition parts.