The stamping forming of laser tailor-welded blank for car door inner panel was simulated based on the Dynaform, stamping process and the deflects that influence the product quality seriously in stamping process, such as the wrinkling, cracking，insufficient deformation and large quantities movement of weld line, were simulated and analyzed. After the comprehensive analysis of wrinkling and cracking, the drawing technological parameters and modular structure parameters were designed using orthogonal experiment. The prioritization schemes were proposed, such as optimum blank holder force, the height of drawing tendon, lubrication condition and so on, which could improve forming quality. The drawbacks of wrinkling, cracking, insufficient deformation and large quantities movement can be greatly improved, when adopting twice drawing forming technology. Practical process design and manufacture show that forming process and the result of numerical simulation experiment fit well.